Every day deserves a better routine
Discover Every Routine cleansers, toner pads, targeted treatments, moisturisers and sun care—curated as one complete Korean skincare wardrobe.
SHOP EVERY ROUTINE →Official Every Routine distributor in Singapore
COCOMO is the sole exclusive distributor of Every Routine in Singapore. Shop with confidence knowing your product is authentic and directly sourced.


This listing includes one 10ml refill cartridge. The compatible reusable main applicator is required and is not included.
Continue focused night care without replacing your applicator
If you already own the reusable 3PDRN applicator, this 10ml refill keeps your routine going without buying another main unit. The concentrated Triple PDRN formula supports smoother-looking texture, refined-looking pores, softer-looking lines, firmness and a brighter finish as your final PM step.
- ✓Refill-only valueReplace only the empty 10ml cartridge and keep using your compatible applicator.
- ✓Five visible concernsOne final PM step supports pores, uneven texture, fine lines, dullness and less firm-looking skin.
- ✓Triple PDRN focusSalmon-derived PDRN, plant-based PDRN and PDRN-coated spicules support conditioning and firmer-looking skin.
- ✓Rich yet lightweightConcentrated moisture leaves a comfortable, non-greasy overnight finish.
Three complementary PDRN components in one concentrated cream
The formula brings together salmon-derived PDRN, plant-based PDRN and PDRN-coated hydrolysed sponge spicules. Together, they provide focused skin-conditioning, moisture and firmness support in a lightweight nighttime cream.
PDRN ingredient testing recorded 43% less measured sebum and 53% less measured UV pigmentation
Human testing of the featured PDRN ingredient recorded a 43% reduction in measured sebum and a 53% reduction in measured UV pigmentation.
The 43% and 53% figures are ingredient-level human-test results for PDRN.
Focused ingredients for texture, tone, moisture and firmness
Sodium DNA (PDRN) is listed at 1.6 ppm, and the formula contains fragrance.
Choose this refill when your applicator is ready for its next cartridge
- You already own the compatible Every Routine 3PDRN Spicule Cream main applicator.
- You want to continue focused nightly care without purchasing another applicator.
- Enlarged-looking pores, uneven texture or fine lines are part of your evening-care focus.
- Your skin benefits from concentrated moisture, firmness support and a brighter-looking finish.
- You prefer a controlled applicator that places a small amount onto selected areas.
Apply the cream as your final evening skincare step
- 1Prepare your skinIn the evening, cleanse and complete toner, serum or ampoule, and moisturiser.
- 2Apply a small amountDispense the cream onto the face or selected areas where you want focused care.
- 3Press in gentlyUse clean fingertips to press the cream into the skin without vigorous rubbing.
- 4Let it settleAllow the cream to settle as the final step of your evening routine.
- 5Build frequency graduallyPatch test first. If you are new to spicule skincare or have sensitive skin, begin 2–3 evenings weekly and increase only while your skin remains comfortable.
For topical use only. Avoid the eye and lip areas and do not apply to damaged or irritated skin. Stop use if irritation is strong or persists, and apply sunscreen during the day.
This listing contains one Every Routine 3PDRN Spicule Cream Refill 10ml cartridge. The compatible reusable main applicator is required and is not included.
Replace the empty cartridge before applying the cream
- 1Remove the applicator tipTwist and remove the pointed tip from the reusable main unit.
- 2Remove the empty cartridgeLift the finished cartridge out of the main unit.
- 3Open the new refillTwist off the protective cap from this 10ml refill cartridge.
- 4Insert the refillPlace it into the main unit with the open end facing upward.
- 5Secure the applicator tipReattach the pointed tip and twist until firmly secured.
Frequently Asked Questions
What is included in this listing?
Can I use the refill without the main applicator?
Will this refill fit another applicator?
Which visible concerns does the cream support?
When should I apply it?
How often should I use it?
What does the cream feel like?
Is it suitable for sensitive skin?
Can I layer it with other skincare?
Does the formula contain fragrance?
Full Ingredient List
Water, Hydrogenated Polydecene, Glycerin, Hydrogenated Poly(C6-14 Olefin), Butylene Glycol, Coco-Caprylate/Caprate, Polyglyceryl-4 Oleate, Isononyl Isononanoate, Niacinamide, Polyglyceryl-6 Oleate, Polyhydroxystearic Acid, Sorbitan Olivate, Disteardimonium Hectorite, Magnesium Sulfate, 1,2-Hexanediol, Sorbitan Sesquioleate, Caprylyl Glycol, Hydroxyacetophenone, Ethylhexylglycerin, Xanthan Gum, Fragrance (Parfum), Adenosine, Hydrolyzed Sponge (286 ppm), Disodium EDTA, Cyanocobalamin (Vitamin B12), Hydrogenated Lecithin, Calcium Silicate, Sodium DNA (PDRN) (1.6 ppm), Nicotinamide Mononucleotide (NMN), Sodium Silicate, Camellia Sinensis (Green Tea) Leaf Extract.
Refer to the product packaging for the latest ingredient list.
Complete Your Every Routine Skincare Routine
Morning: Cleanser → Toner Pad → Choose Liftox-Seal Gold Ampoule or Estro Ampoule → Moisturiser → Sunscreen.
Evening: Cleanser → Toner Pad → Choose an ampoule → Moisturiser → 3PDRN Spicule Cream as the final face step.
Extra care: Add the Glossy Collagen Fill-Up Mask after toner whenever you want intensive hydration and glow.
Refill note: This refill is not a separate skincare step. It requires the reusable applicator shown in the 3PDRN Spicule Cream 10ml card below.
STEP 1 · CLEANSEBlack Salt Cleansing Powder 50gLift away daily buildup so your next skincare steps apply to fresh, clean skin.SHOP CLEANSER →
STEP 2 · REFINEGraphene Peeling Toner Pad 220gSmooth, hydrate and prepare the complexion for the skincare steps that follow.SHOP TONER PAD →
STEP 3 · AMPOULELiftox-Seal Gold Ampoule 35gGive skin rich firming moisture, smoother texture and a luminous golden finish.SHOP LIFTOX-SEAL →
STEP 3 · ALTERNATIVE AMPOULEEstro Ampoule 30mlChoose a lightweight conditioning ampoule for skin affected by monthly changes.SHOP ESTRO →
STEP 4 · MOISTURISE100 Gel-in-Ball Repair Cream 70gSeal in your ampoule with comforting moisture and barrier-supporting care.SHOP CREAM →
STEP 5 · REQUIRED APPLICATOR3PDRN Spicule Cream 10mlThis refill requires the reusable applicator included with the standalone 10ml cream.SHOP APPLICATOR →
STEP 5 · AM PROTECTGlutaPDRN Sun Cream SPF50+ PA++++Finish the morning routine with high UV protection and glow-supporting care.SHOP SUNSCREEN →
OPTIONAL · INTENSIVE MASK CAREGlossy Collagen Fill-Up MaskAdd a close-fitting hydrogel treatment when skin needs concentrated moisture, cooling comfort and glossy bounce.SHOP COLLAGEN MASK →
DAILY WELLNESS RANGEEvery Cut Diet JellyExplore the convenient yogurt-flavoured jelly format in the wider Every Routine range.SHOP EVERY CUT →
DAILY WELLNESS RANGEMealdang TeaComplete the range with a smooth, caffeine-free herbal tea for a comforting daily cup.SHOP MEALDANG TEA →
Detailed Product Images
Refill-only listing: Product materials may show the compatible reusable applicator. This listing includes only one 10ml refill cartridge; the applicator is not included.
Ingredient-data note: Ingredient research images describe testing of the featured PDRN or spicule ingredient.






























